TREATING DRY EYE DISEASE


Evaporation may impede the success of current DED treatments1,2

Current DED treatments, including lid hygiene, in-office procedures, and over-the-counter products, may help address MGD (meibomian gland dysfunction), a key upstream driver of excessive evaporation.3-6

Treatments may fall short in directly addressing tear
evaporation due to3-5:

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Poor patient compliance
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Suboptimal symptom relief
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Patient discontinuation

Not all prescription eye drops for DED are the same7-11

Most Rx treatments leave excessive evaporation unaddressed.3,7-11

Depiction of excessive evaporation not being targeted with current treatments Depiction of excessive evaporation not being targeted with current treatments

Anti-inflammatories and tear stimulators may be insufficient to resolve symptoms of DED, and low rates of compliance and adherence have been observed.12,13

In a retrospective insurance claim study of 6537 cyclosporine patients and 3235 lifitegrast patients,

Discontinued treatment icon
Discontinued treatment icon
with lifitegrast or cyclosporine
within 12 months12
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Simply put, dry eye disease is the number one medical condition that motivates patients to see their ECP—and it will only grow.14

—Paul Karpecki, OD, FAAO
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Evaporation can hinder treatment efforts, and addressing it may provide relief to more patients with DED1-3

If evaporation is not addressed, signs and symptoms of DED may chronically persist.15
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Review select literature expanding on the
treatment of DED

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Real-world treatment patterns of cyclosporine ophthalmic emulsion and lifitegrast ophthalmic solution among patients with dry eye

White DE, et al.
Clin Ophthalmol. 2019
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Emerging strategies for the diagnosis and treatment of meibomian gland dysfunction: proceedings of the OCEAN group meeting

Geerling G, et al.
Ocul Surf. 2017
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TFOS DEWS II management and therapy report

Jones L, et al.
Ocul Surf. 2017
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Impact of dry eye disease on work productivity, and patients’ satisfaction with over-the-counter dry eye treatments

Nichols KK, et al.
Invest Ophthalmol Vis Sci. 2016